https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29909 P < 0.001) were found between ALDH expression and various motility parameters of stallion spermatozoa including the percentage of progressive (r = 0.79) and rapidly motile (r = 0.79) spermatozoa, whereas repeated measurements over 24 h revealed highly significant correlations among progressive motility loss, 4HNE accumulation, and ALDH expression (P ≤ 0.001). ALDH inhibition resulted in a spontaneous increase in 4HNE levels in viable cells (21.1 ± 5.8% vs. 42.6 ± 5.2%; P ≤ 0.05) and a corresponding decrease in total motility (41.7 ± 6.2% vs. 6.4 ± 2.6%; P ≤ 0.001) and progressive motility (17.0 ± 4.1% vs. 0.7 ± 0.4%; P ≤ 0.001) of stallion spermatozoa over 24 h. Similarly, inhibition of ALDH in 4HNE-challenged spermatozoa significantly reduced total motility over 4 h (35.4 ± 9.7% vs. 15.3 ± 5.1%, respectively; P ≤ 0.05). This study contributes valuable information about the role of the ALDH enzymes in the maintenance of stallion sperm functionality, with potential diagnostic and in vitro applications for assisted reproductive technologies.]]> Wed 11 Apr 2018 16:45:10 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:2266 Sat 24 Mar 2018 08:26:55 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:11205 Sat 24 Mar 2018 08:12:44 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17995 Sat 24 Mar 2018 07:56:35 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41 Sat 24 Mar 2018 07:42:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27065 Sat 24 Mar 2018 07:25:20 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40400 Mon 11 Jul 2022 13:55:46 AEST ]]>